Thursday 25 April 2024

Yeasts with Galician DNA

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When Simon and Noelia decided six years ago to open a small Albariño winery in his native Soutomaior they did it conscientiously . He, an industrial engineer, and she, an economist, had no experience or relationship with the world of wine but had the ambition to make the “perfect” plantation to create the winery Noelia Bebelia . They hired a consultant team including researchers from the University of Vigo, the CSIC, and enologists. After studying the characteristics of the ground and the incidence of wind and sun on it, they decided what ground would be used, what kind of vide would be planted and even the distance between the feet of vines. They planted 6,000 vines in three hectares of land on the slopes of the Verdugo river. “The idea was to do it with all the knowledge of Galician agronomist staff to create the perfect plantation ” explains Simon Barcia, head of the winery beside his wife.

Noelia Bebelia.
Noelia Bebelia.

But four years ago, the time of the experimental vinification and behaviour test of the grape came and they found a problem that got them away from that perfection that marks the whole process: the yeasts. “Or we choose the trade ones , which come from France, Italy or the United States , or we choose the traditional way of spontaneous fermentation with yeast own grape “.

The process is not easy or quick or cheap. It will begin in September or October with the grape harvest and the making of the first must. All these samples will be sent to one of two laboratories in Spain, in Barcelona or La Rioja, where DNA studies on different yeasts, that are in the skin of grapes, are made. Then non-native yeasts will be discarded as well as trade ones with their “killer factor” because they get imposed on local ones. Only 20 or 30 will be selected from all of them and small fermentations will be made to compare their behavior and results. The best yeast will be chosen which will be used for the first harvest and to be retained in glycerol in the laboratory. The process will last about two years. It is becoming now affordable for small wineries, as the payout is about 14,000 euros. It is unusual in Galicia because only large wineries could afford it before DNA Analyses became cheaper.

The aim of Bebelia is to obtain a unique wine on the market, which is  planted on their land on Verdugo river shores where the raw material, grapes and yeast come from its ground. It is unusual in most of wineries using trade yeasts from other regions . In two years, after many tests and laboratory hours, Noelia Bebelia may present the fruit of his obsessive viticulture.

A diabeticʼs diary in one shot

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Insulin therapy is often a cumbersome process for the diabetic who runs the risk of neglecting their treatment. Jose Luis Lopez has been experiencing it firsthand from age 19, but he did not find a customized solution until 2013, when he created the prototype of a device that replaces the notebook where the diabetic writes each insulin injection.

Insulclock es especialmente útil para enfermos dependientes o niños
Insulclock es especialmente útil para enfermos dependientes o niños

The result is called Insulclock. The diabetic tired of carrying a book is today one of the CEOs of a developing project. The idea consists of a small suitable device to place anywhere in the insulin pen. As soon as the drug is administered, the device sends data about the doses to an application so patients do not need to worry about anything else.
The time, amounts, temperature and state of insulin are recorded and available both to the doctor and to the patient at the same time the patient has pricked. If all project objectives are met, it could be on the market in the first half of 2016.
“It involves above all quality of life, because it allows to automate the entire prescription process of quality insulin administration with only one puncture. It can create a number of useful alerts,” comments Jesus Perez, director of Insulclock in Galicia, on a project that is currently being developed at the Center for Entrepreneurship ‘Galicia Open Future‘ of the City of Culture in Santiago, a collaboration between the Telefonica Foundation and the regional government, Xunta.
In a few months when the crowdfunding, which 12 Insulclock supporters have just promoted, finishes the device will be tested in hospitals in A Coruña and Santiago, and at the University of Atlanta, in the United States.
“There is nothing like this on the market today, existing applications work to enter the data manually,” explains the project manager in Galicia, who emphasizes that the idea comes from a group of professionals with very different profiles, like doctors, such as Clotilde Vázquez, head of the Clinical Nutrition Service of Ramon&Cajal Hospital, engineers like Jesus Arenas, one of the CEOs of Insulclock or nurses, such as Araceli Martin, from the Jimenez Diaz Foundation.
“Everyone tells us Insulclock improves the quality of life greatly. This tool allows daily and more precise control, because it is very important that chronically ill people respect the treatment. Forgetfulness can be very serious,” explains Perez.

Print your jaw for dental practice

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This plastic model of the patient’s skull or teeth where an implant will be placed has been a kind of luxury for both doctors and patients until now. Getting a reliable model of a human body part used to be expensive and the dentist would be wary about ordering it because only a few customers could afford it, even when such models have been useful for preparing a surgery or when explaining to the patient what would happen in the surgery room. But the development of technologies such as 3D printing have come nowadays to improve the procedure. That is, at least what two partners of DQbito believe, Lago González and Manuel Angel Iglesias, industrial and physical engineer, respectively, who show the world the virtues of biomedical engineering. Both partners are from Baiona and they sell affordable high quality anatomical plastic models of the human body to doctors from many different countries worldwide. These models have become available via the 3D printing from a single TAC downloadable from their website.

Uno de los modelos en plástico que imprime DQbito
One plastic model of DQbito.

The benefits of these plastic jaws where a dentist can check the best position of a prosthesis are noticeable when one looks at the low prices and the clients bill. Nowadays one of these models can cost only as much as 50 euros. It is very cheap if you thought it’d cost 500 euros in the past.  Doctors alike will not hesitate when it comes to using this device.
“We work mostly with dental specialists and maxillofacial surgery through medical imaging tests such as CT scans. The doctors themselves upload their files onto our website and we process them according to the specific demands from each of them. So we get an exact model of the person anatomy, both bones and soft tissue”, explains Manuel Angel Iglesias, one of the two partners of DQbito. DQbito was born three years ago after the two founders attended a course at the University of Vigo which sparked this business idea. Today the model is sold to European countries like Germany, Italy and France, and Spain, and coming soon to Mexico through a local partner.
The result is a tool that makes easier the doctors’ daily work. “This is a very accurate  model to check surgery prosthesis before using them on patients,” he concludes.

A portable electrocardiogram and instant lifesaving

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The patient will not notice it while walking, sleeping or having a coffee, but a small device of eight centimeters and two electrodes attached to the skin of the chest is monitoring the heart second by second and, if there is any incident in the heart rate your doctor will receive an excerpt from the resulting electrocardiogram in real time. The sensor, part of the e-Heart project developed by CONEXIONA Telecom in Orense, has the power to cause an instant alarm in case of atrial fibrillation, a heart disorder sometimes asymptomatic but capable of causing the patient a massive stroke. It is a quick reaction to a difficult problem to detect and no solution yet on the market, since other available monitoring options work as mere recorders and they are only analyzed after the fact.

La arritmia con fibrilación auricular es a menudo difícil de detectar
La arritmia con fibrilación auricular es a menudo difícil de detectar

CONEXIONA Telecom Firm, based in the Technology Park of Galicia-Tecnópole in San Cibrao das Viñas, leads the consortium of six companies: Optare, Quobis, Hacce, Tecsoftcom and Gradiant and Hospital Complex Foundation in Coruña that made possible the prototype e-Heart. Wireless and with a single branch, so little intrusive, the sensor can collect vital data on the behavior of the heart and transmit them to cardiologist in case of trouble. “It is connected via Bluetooth to a smartphone and our application analyses the data and interprets the complex QRS that measure if there is an arrhythmia with atrial fibrillation”, explains Carlos Sande, biologist and research director by CONEXIONA, founded in 2006 and specialized in development and solutions JAVA for tools that like this one works in real time. A telephone application and a medical management platform are able to do the rest: ask the patient for his symptoms, extract data from the anomaly, send them to a cloud system and  the doctor will be informed quickly.

e-Heart is connected via Bluetooth to a smartphone

“It allows the patient wear it until fibrillation is found. The idea is to prevent. Knowing whether the problem exists or discard it” says Sande. The tool uses a system of WebRTC, which streamlines communication between doctor and patient through the browser without downloading software continuously. In addition, e-Heart allows the analysis of collected information and its processing is performed from start to the end in the mobile application, so only abnormal fragments of the electrocardiogram will remain saved.

New vaccine to fight TB´s, The Brainchild of O Porriño

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More efficient than its predecessor the BGC –bacillus Calmette- Guérin, which in the early 20s of the past 20th century was the first vaccine at the Pasteur Institute against TB (tuberculosis)- is the brainchild of O Porriño and Zaragoza pharmaceutical companies. This is what MTVBAC will turn out to be, the name of an experimental vaccine against the Mycobacterium tuberculosis, the most common bacterium of the lung tuberculosis whose future is in the hands of the biopharmaceutical at O Porriño, Biofabri. So far this 1 century old vaccine has shown a 50% resistance in adults.

Patógenos causantes de la tuberculosis.
TB (tuberculosis).

The problems to protect the adult population from TB could be reduced considerably in a few years. Biofabri biopharma, a company with headquarters in O Porriño and a subsidiary of CZ Veterinary – the predecessor of Zeltia– funding the MTVBAC clinical trials with newborn babies in South Africa and together with the European initiative against Tuberculosis (TBVI). They will have the last word about whether the vaccine, the outcome of a long time research with the Group of Genetics of Microbacterias at the university of Zaragoza, will end up as the new protector against TB´s. The company from O Porriño will be likely responsible for the worldwide distribution of the future vaccine if research shows positive results.
The clinical trials have been ongoing for a month or so in Cape Town and are supposed to be one of the most ambitious projects of Biofabri and a milestone in this type of research worldwide. This company has been focused, since its inception in 2008 and as subsidiary of CZ Veterinary, on the manufacturing of medication and drugs for the healthcare system and has remained an integral part of a 100% Spanish corporation, C&B Group, this company has settled at Torneiros (O Porriño) since 2009. This company has a strong research team of 150 people.

The mussel raft that became a power station

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The sun hides, the wind is capricious, the dams dry up… Renewable energies have to face the cravings of their own natural resources, virtually  inexhaustible, but each of them is non negotiable. It is pretty different the case with tides. invariably, a great deal of water streaming for over 6 hours from the sea to the coast to change direction at the same time. And thus, once and again, constantly, in a predictable way and speed, which at given locations on earth go over 10 nots ( 18 km/h). It’s such a tempting option so as not to turn it into power or electricity.

The floating feature of this Galician trimaran makes it easier to maintain it

That’s what the Magallanes Renovables project is all about, a company based in Redondela, which have decided to press on with a large amount of megawatts of power coming from sea tides. And in order to achieve this objective, at Cardama shipyards in Vigo, a prototype has been put on display,  a floating trimaran of over 350 tones with 19 mt propellers attached to it. Its challenge will be to make the best of water streams at an angle of 270 degrees.
The Magallanes project is backed up by a big ally : its main feature is the floating device. It’s an all Galician project, which solely oversees the estuaries and the mussel rafts . Likewise , the trimaran  of Magallanes Renovables is floating at the top of the sea but anchored to the bottom with a lot of maintenance benefits. It does not need any big time pillars or infrastructure. It’s simply an efficient system of anchorage, which allows to take advantage of the top speed of sea tides and currents close to the surface of the water.

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Tests on a prototype scale.

“Maintenance has always been the Achilles heel of this sort of project. We have something different here, our system allows anyone on board , to access the facility or to fix it quickly in situ if any problem arises. ”, explains  Pablo Mansilla, technical coordinator of the project. This innovative device has overcome already a plethora of trial tests 2014. They tested a prototype of 1:10 scale. Now they’re at the very end of the assembling and building of the first real time and place product. Before the years finished this device will face the music at sea.
“Tides are now in an initial same state of development as  winds were 20 years ago; this is the future ” says a company’s PR. This device like the one made in Vigo can power up to 2 Megawatts of electricity. “A park with over 200 rafts would be enough to provide with power to a city  like  Vigo”, same energy is necessary.
The Xunta has backed up this project through the Galician  branch of the I+D, and  specially the 40 college and technological institutions researchers have joined forces in this project. Their objective is to open up new doors to this industry. This time, Galicia whose beaches open a large space between high and low tides. The most important thing here is the knowledge and the Industrial applications.

Chestnuts In Allergies Out

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We have a clear and fresh picture of chestnuts because of the magostos (Galician chestnut seasonal party), but out of season chestnut consumption has been decreasing. They were a part of our diet before the dawn of the potato and corn brought to Europe from America. In the days of the industrial revolution, people left rural areas to move to the cities, chestnuts were very popular and now chestnuts are back in the menu, in fact theyre back to mitigate the hundreds of allergies which plague the guts of the current city dwellers. Basically, no one is allergic to chestnuts, and the food industry has realized that chestnuts are healthy and they have begun to bring them back to the consumer.

The company has been exporting almost all of the chestnut harvest

This idea has popped in the head of the promoters of the project Senalergal, a joint effort of 5 Galician companies to prevent bad digestions due to allergies. The branding is led by Alibós, Daveiga, Montiño, Prestes, Kiwi Atlántico and Bioselección, specialized, respectively, in chestnuts, cookies, cold cuts, cheeses, kiwis and organic produce. The project, which has been financed by the Axencia Galega of Innovación via the program Conecta Peme, and has allowed these companies to produce pastries and cold cuts or delicacies gluten free and cheeses without lactose. That’s great news to those of you who are usually allergic to these foods.
Alibos4At Alibós (the acronym stands for Alimentos del Bosque-Forest Foods), they looked at chestnuts way back in the 80s; after an initial stage of mushroom harvesting, they have now become one of the major producers in the Galician chestnut trade in Spain. Almost, all of the chestnuts purchased and processed by this company, collected and harvested, are handpicked, peeled, frozen and exported overseas.
Alibós processes over 6 and 7 million kilos of chestnuts per year. They have to purchase so much chestnut that the Galician production is not enough and have to look at places like Portugal or Cáceres to acquire even more. So far, they have had to purchase chestnuts but now they have been working on developing and harvesting this produce in areas like A Ulloa. Firstly, This will help bring the chestnut groves back to life. Secondly, they are going to attempt to get both symbiotic partners together back again, chestnut trees and mushrooms. Moreover, this will help bees return to the forest and thus boost chestnut pollination. The ecosystem will thrive again should this one-of-a-kind-idea prosper. The chestnut crops range from such places like Lalin and Agolada to Os Ancares, The sweet revenge of the chestnut is on its way.

The small science of big projects

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Lets start off from the beginning. Behind this complex name of nanotechnology we find the whimsical branch of nanotechnology with applications or biological or biochemical usages.  This is the field, in which Nanoimmunotech is breaking some ground, a spin-off of the Vigo and Zaragoza colleges, with such varied and useful developments as locating tumors, quick salmonella detection or the production of pregnancy tests and water treatment or filtration with ozone and gold nanoparticles.

Bioconjugation, nanodetectors and nanotoxicity,big fields in this trade now

“Our company was set up in 2009 as a consequence of a large body of knowledge which came from the field of nanobiotechnology and the new business opportunities which were out there”, explains their manager, Rubén Santos. The Centro de Investigaciones Biomédicas de Vigo (Cinbio) –Biomedical Research Center, and the Instituto de Nanociencia de Aragón (INA)-Institute of Nanoscience, joined forces to develop new tools, which can be discerned clearly. The participation in a cooperative effort and projects of the 3 main corporations Interconnecta, for instance “a clear example of great success in this type of research of triple helix: institutions, companies and colleges”.

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Rubén Santos, CEO of Nanoimmunotech.

Nanoimmunotech, with their headquarters in Vigo and Zaragoza, have undertaken joint projects in order to develop a vaccine against cystitis, the detection of substances in water filtering and treatment plants or stress level detection in animals before putting them down through sweat and saliva assessment with the expertise of companies like CZ Veterinaria, Copasa or Coren. This way an I+D has been developed and is still in progress under the management of 14 employees. “We are basically a company dedicated to I+D; it’s the main purpose of our expenditure, which I can tell you we spend around 50% of our total budget”, says Santos.
The bioconjugation is one of the 3 main fields, in which the company works around. Another line of work of our company is aimed at the field of nanobiodetectors: a live element is detected whether it be water or air or whatever in the bloodstream, for instance. The third line of research of Nanoinmunotech is nanotoxicity, which offers great reliability within product analytics that employ nanoparticles. Within all this plethora of services, Nanoimmunotech has been consolidated as a demonstration of the importance to move into the world of commerce the knowledge of universities worldwide. Or better said, this is the proof that knowledge can turn into a profitable business and be a part of the economy.

Sea greens make it to the gourmet table

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There are seaweeds, with such an intense flavor in our oceans, that remind us of crustaceans and they even taste way better than the traditional seafood. There’s one unique Galician seaweed, which is called “alga percebe”(barnacle seaweed) and when you taste it, is easy to tell why it is so unique. Galicia is so green and productive and not only its land greens are so good but also its sea greens are delicious. It’s seafood is not the only rich and gastronomic delicatessen but its sea and coast are populated by a plethora of algae and seaweeds, 25 out of over 200 seaweed species are of great nutritional potential for the top chefs and yet unknown to many.
It’s all a cocktail of vitamins minerals and oligo-elements which are highly popular in all Galician kitchens and are brought to the table by Grupo Nove. This company is at the avant guard of the Galician cuisine. They’re asking for seaweed as the protagonist of the new dishes.

Some seaweeds have such an intense flavor that are a match to the famous Galician seafood

To unravel, recollect, process and preserve this potential and traditional dish without losing its original taste and properties Sergio Baamonde and Alberto Sánchez have been putting a lot of effort and ingenuity into it for over 3 years from the sea coast of Ortigueira. It is this sea line the most dangerous , rugged and wild of A Coruña.
Ferrol pals and school mates since childhood; the latter studied Marine Biology and the other Sea Sciences. After walking different paths for years they were reunited in 2012 due to a project about making the best of sea greens as they coined the term. This is a food which is completely ignored in Spanish cuisine but a deli dish in Asian cultures.
Mar de Ardora 3“100% traditional , organic and Galician”, this is their motto and  Conservas Mar de Ardora, their brand. Ardora is the silvery shine which is visible due to a unique sort of microscopic cold water sea weed, which also relies on certain tides and northern wind. The moon shines on the  salty water with magic qualities. And under this commercial umbrella they offer green, purple and red sea weeds or “nori” which come fresh, dehydrated or canned. They’re suprisingly whimsical like the spicy sea spaghetti , or the sweet quincy Kombu weed, and incredibly delicious to the most demanding palate.
“Mar de Ardora S.L. is a dream come true”, say their marketers, “it’s the starting gear of a traditional food canning factory which work with different types of vegetable marine foods”.
Three years ago they managed to open up this canning company in the industrial estate of  Rego-Cuíña (Ortigueira). And now Sergio and Alberto have taken off in a niche seaweed market which very few Galician companies can compete with them. The main difference is that they offer fresh and hand processed  seaweed which preserve the produce and texture better. Moreover, they’re organic certified (Craega).
These two young entrepreneurs, pushing only their forties have to dive literally speaking to get their produce. Both of them are by now the only owners, partners  and employees of a self managed and profitable company.

Netex: a digital educational and job training factory 

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Spain, UK, India, Mexico and coming soon to the USA. The Galician company Netex is now gaining a piece of the international digital pie with its new training apps. And it’s doing it with the back up of the Spanish departments of commerce and trade. The company just recently has swept an award as the most innovative PYME (stand for small and medium sized company in Spain). The key to its success is due to the forward thinking of ever innovating, creating new apps and recruiting talent.

Parte del equipo de Netex encargado de la digitalización de contenidos
The team responsible for digitalization.

Netex offers solutions to companies publishers and educational institutions worldwide. This includes mobile training apps and platforms to help train company associates and workers (face to face, online and blended), solutions related to digital content, customised catalogues and authored tools for self publishing. Its portfolio is vast and includes the work of consultants, instructional and graphic designers or engineers. The company has also raked several awards that acknowledge its long standing innovative record. They develop all apps and digital content from their headquarters in Galicia together with its partners in Sweden, Germany, Ireland, Italy, Netherlands, New Zealand, Australia or Uruguay. A milestone for Netex has been the international award won at the  prestigious  Learning Awards by the Learning and Performance Institute, as a runner up within the “E-learning supplier of the year 2015″. Also we must mention the worthy bronze award won as “ e-learning developers of the year 2014”.
Likewise, the educational platform developed by Netex has hit it off also with renown Spanish publishers like the one with the UNO system –a collaborative effort with Santillana publishers. UNO has reached a whooping figure of 1 million users in South America.
learningMaker NetexIn the scope of training companies, Netex offers a LearningCloud solution, a management platform called LMS (Learning Management System) with a plethora of apps in the CLoud for organisations with need in L&D (Learning & Development), it helps manage knowledge generated in a unique virtual environment, fostering collaboration via corporate social networks and using tools for the creation and management of multi device management accessible online y offline.
Likewise, the foundation of the company lies on the successful LearningCoffee, a content solution of customised catalogues based on soft-skills with over 200 titles.

New ways of innovation

Within the Big Data and Learning Analytics fields, Netex has been developing the new ‘T-Didacta’, project which attempts to solve all the issues coming from mobile devices like tablets and learning digital environments in classrooms.
Regarding the Artificial Intelligence“the progress comes from the latter”, that is to say, “intelligence applied to predicts school failure and how to advise students on contents without the interference of a third party, and also the adaptation based on participation”, says José Ramón Mosteiro, the CTO of Netex.
Lastly, the augmented and virtual reality is one of the fields which is generating most expectations. Mosteiro gives an example: “an application of  PNL with Google Glass, that is able to cut down to zero the fear of public speaking. Seemingly, it does not have a big impact on education but if you have to get up and give a speech based on an end of term student project… This is well proven … It works!”.